First Zinbryta Injection Yesterday

Yesterday I finally had my first injection of Zinbryta. It took months to get it approved and sent to me but it finally happened. So that was a little relieving. But then I was nervous it was going to make me feel like crap much like Rebif did. After talking to a lot of people in support groups on Facebook my worries were put at ease a bit. It seemed like the most common issue was dry skin or an injection site reaction. Well, I injected around 8am yesterday and over 24 hours later no problems at all. No dry skin, no injection site reaction, nothing. So I am happy it went so smoothly.

Now I am just worried about my monthly labs. Zinbryta messes with your immune system (it’s a monoclonal antibody like Tysabri and Lemtrada) so there are all these warnings about infection and getting sick and stuff like that. When my white blood count (WBC) has already been pretty unstable lately will this knock it back down? What then? Stop Zinbryta? And then what? Because pretty much all MS therapies affect the immune system so will that mean that Lemtrada screwed up my ability to use any other therapy while seemingly having done nothing beneficial for me? Well maybe (and hopefully) none of that will happen. Hopefully all my numbers will look good and I can remain on this treatment.

Oh yeah, I have been getting so many phone calls from Biogen and Biogen nurses about Zinbryta. It’s driving me nuts because it is all stuff I have heard 1,000 times before since the day I was first diagnosed with MS and started Copaxone. No, I DO NOT NEED injection training. Thank you though for calling me 3 days in a row to ask. You never know when someone might get smacked in the head with a frying pan 5 minutes after your first call and forget how to do something they have been doing for years. So the constant asking? That, THAT is what we call being proactive. And yes, I know there is a nurse on call 24/7 that I can call with a question about Zinbryta and be told to ask my doctor. I know. I am not new to this. But again, thank you! Take care now, bye-bye then!

Anyway, I also saw my primary care physician (PCP) on Wednesday and he agreed that I should resume taking Zoloft which I pretty much already knew but needed confirmed by an actual doctor. He said my weight loss issue could very well be related to me stopping Zoloft; all the stress, depression, and anxiety I have been experiencing could not only affect my appetite but the chemicals in my brain have obviously changed since stopping a medication I had been on for years so chances are that would affect something! I also asked for some sort of referral to a therapist so he also gave me that. I have to call on Monday and see if they take my insurance and if they do see if they can get me in this year because I have always heard it takes FOREVER to get in with a therapist. We will see but that is what’s going on in my life right now. Nothing fun. Well… I DID get my taxes done yesterday so I guess there is that!

Matt Allen G

I was diagnosed with Multiple Sclerosis (MS) in 2010 at the age of 20. It's been a battle ever since and I have always shared my story and struggles online!

5 thoughts on “First Zinbryta Injection Yesterday

  • April 15, 2017 at 1:06 pm
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    Many of the medications we take supress our immune systems. No news there but the meds allow bacteria to thrive inareas that are seen in immunocompromised patiebts (like me). These infections can go on for decades without being discovered. My sinus infecttions were clearly seen on my brain MRI. We feel like our MS is getting worse but when the immunocomprosmised person takes an antibiotic those symptoms can resolve dramaticly. Sinus infections are common but the antibiotics can resolve a urinary tract infection or alter gut bacteria as well. Try consulting with an immunologist at a nerby university. As for seeig an LCSW your best bet is a University or well funded medical services like Mayo or Cleveland Clinic. Hang in there Matt. It took me 20 years to find a sweet spot with my meds.

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    • April 25, 2017 at 12:29 am
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      Hi Matt! I pray that Zynbryta continues to work well for you!! My 30 year old nephew in-law was also diagnosed with MS & I would like to know if there are any recommendations you can give him?

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      • April 30, 2017 at 3:56 pm
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        diet. I WISH I took that more seriously when I was first diagnosed. eat well and exercise every day because in the long run it will pay off.

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  • April 29, 2017 at 10:29 pm
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    Hi Matt,

    I do not have MS so I do not know what you are going through entirely. However, I find your posts very enduring, real, convicting, and passionate. Thank you for writing these posts so that we can have a better understanding about your struggles and daily concerns. It is very eye opening and educational and it spurs people like me to want to find ways to help support research for MS. Overall, it seems like so much can go wrong so quickly, so I found it to be such a relief to read and know that your first injections were successful! Although the future continues to be unknown, I pray your monthly lab results will also be good news. Keep updating us with your progress and keep persevering. I hope the therapy works out because you deserve it!

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    • April 30, 2017 at 4:18 pm
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      Thank you, I will be keeping everyone posted for sure. I am REALLY eager to see my lab, I have not got to see them in a long time and now I just started another drug that may greatly affect them! Fingers crossed though.

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