MS Therapy – Gilenya (Fingolimod) Oral Medication

Name: Gilenya (Fingolimod)

Type: Oral Medication
Approved: 2010
Approved For: Reducing the frequency of MS flare-ups (relapses) in patients with Relapsing Remitting Multiple Sclerosis (RRMS) as well as reducing the long term disability effects of MS.
Reported Relapse Reduction Rate: 54% Compared to placebo
Recommended Dosage: 0.5mg orally once daily (with or without food)
Schedule: Daily
Storage: Gilenya capsules should be stored at 77F (25C)
Support Team: Go Program – 1-800-445-3692 – Offers information on paying for medication, information about the first day on medication, forms to start Gilenya, reminders, motivation, and support.

 How Gilenya Works: Gilenya is thought to work by preventing lymphocytes from attacking the central nervous system by reducing the number of lymphocytes in the blood. Lymphocytes are the T-cells that our immune system uses to attack foreign substances or in MS, the immune cells that attack the myelin sheath.

Common Side Effects:  Headache, influenza, diarrhea, back pain, abnormal liver tests, and cough.

In April of 2012 Gilenya added that there is a possible heart risk to the label. It is now recommended that you get an ECG (electrocardiogram) before and after your first dose which should be taken in the doctor’s office so your heart can be monitored for 6 hours.

Gilenya can also affect your immune system’s ability to fight off infection.

Serious Side Effects: Get medical help right away if you have any very serious side effects, including: shortness of breath, chest pain, severe dizziness/fainting, slow/irregular/fast heartbeat, unusual tiredness/weakness, eye pain/sensitivity to light, vision changes (such as blurred vision, blind spot/shadows in the center of your vision, color changes).

Possibly PML Infection?  READ MORE HERE

This is not a complete list of side effects

FDA Prescribing Information
More Complete List of Side Effects

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