Medication – Nuvigil

Nuvigil (Armodafinil):
In MS this medication is typically used for severe fatigue.

“Armodafinil decreases
extreme sleepiness due to narcolepsy and other sleep
disorders such as difficult/irregular breathing during sleep (e.g.,
obstructive sleep apnea/hypopnea syndrome-OSAHS). It is also used to
decrease sleepiness due to work schedules that interfere with a
normal sleep routine (shift work sleep disorder-SWSD).

It is not known how armodafinil works to increase
wakefulness. It is thought to work by affecting certain substances in
the brain
that control the sleep/wake cycle. Armodafinil does not make up for
lack of sleep. It should not be used to treat tiredness or hold off
sleep in people who do not have a sleep disorder” –

Matt: This was the best medication ever prescribed to
me, it worked so well! I was alert and mentally awake! Once I started
to not need it as much it did effect me poorly… It felt like my
heart was racing and it felt like I was stressed… So I had to stop,
but again, my fatigue has not been so bad so I think it was just too
much for what little fatigue I have compared to a couple months ago!

Possible Side Effects:

  • Headache
  • nausea
  • dry mouth
  • anxiety
  • dizziness
  • difficulty sleeping
  • signs of infection (e.g., fever, persistent sore

  • mental/mood changes (e.g., agitation, confusion,

  • rare thoughts of suicide),

  • unusual tiredness

  • dark urine
  • yellowing eyes/skin
  • severe abdominal

  • chest

  • fast/pounding/irregular

A very serious allergic
reaction to this drug is rare. However, stop taking armodafinil
and seek immediate medical attention if you notice any of the
following symptoms of a serious allergic reaction:

  • rash/hives
  • skin blisters/peeling
  • sores in the mouth
  • itching/swelling
    (especially of the face/tongue/throat)

  • severe dizziness
  • trouble

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