Steroids and Multiple Sclerosis: Oral Prednisone

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Note: As I’ve said 1 million times and as I will continue to say, I am not a doctor, I have no medical degree of any kind, I only have my personal first hand experiance1 You should always talk to your doctor about any concerns or questions you may have regarding medication!

So today I want to talk about steroids and their relation to multiple sclerosis. Steroids are used to help overcome flareups or exacerbations in MS. Steroids come in pill form (Prednisone) or can be administered in high doses intravenously (Through an IV) but today we will be talking about oral Prednisone.

 The Number One Question:
Will they make you buff? Ha ha I  get this all the time, so let me knock this one out of the way first. No! These are not horse hormones, they are not the kind of steroids that athletes take! Although, one possible side effect is weight gain but everyone is different…

So What Are These Steroids?
The most commonly prescribed pill form of steroids for medical use is Prednisone which is part of a drug class known as “corticosteroids”. These steroids are man-made drugs designed to replace cortisol, a natural hormone produced by the adrenaline glands. This hormone is naturally released in response to stress and to low levels of blood glucocorticoids. Besides increasing your blood sugar, cortisol reduces inflammation and suppresses your immune system.
Though Prednisone can help speed up your recovery through an exacerbation it does not necessarily fix the problem, that is why people with MS must take disease modifying medications such as Copaxone. Rebif, Tysabri, or Gilenya. Steroids are mainly used to help conquer an MS exacerbation by reducing inflammation of the central nervous system (CNS). It helps patients achieve remission!
How long do steroids take to work?
Results very depending on the person and the extent of your exacerbation. You may notice results within a week or a couple of weeks dependingon how much you are on. Again, everyone is different.After taking it a few times you will learn how it work for you!
Possible Side Effects
  • headache
  • dizziness
  • difficulty falling asleep or staying asleep
  • inappropriate happiness
  • extreme changes in mood
  • changes in personality
  • bulging eyes
  • acne
  • thin, fragile skin
  • red or purple blotches or lines under the skin
  • slowed healing of cuts and bruises
  • increased hair growth
  • changes in the way fat is spread around the body
  • extreme tiredness
  • weak muscles
  • irregular or absent menstrual periods
  • decreased sexual desire
  • heartburn
  • increased sweating

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately!!

  • vision problems
  • eye pain, redness, or tearing
  • sore throat, fever, chills, cough, or other signs of infection
  • seizures
  • depression
  • loss of contact with reality
  • confusion
  • muscle twitching or tightening
  • shaking of the hands that you cannot control
  • numbness, burning, or tingling in the face, arms, legs, feet, or hands
  • upset stomach
  • vomiting
  • lightheadedness
  • irregular heartbeat
  • sudden weight gain
  • shortness of breath, especially during the night
  • dry, hacking cough
  • swelling or pain in the stomach
  • swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
  • difficulty breathing or swallowing
  • rash
  • hives
  • itching

SIDE NOTE: I have heard that ibuprofen (NSAID) should not be taken with Prednisone because both medications can possibly cause gastrointestinal problems and together both medications would increase your chances of having issues. 


4 thoughts on “Steroids and Multiple Sclerosis: Oral Prednisone

  • October 29, 2010 at 9:18 am

    Steroids for Sale.
    Men of muscles are also using Winstrol – a brand name for stanozolol that is an anabolic steroid that helps muscle growth. Athletes who want to improve their strength and endurance can mostly try these steroids.

  • October 29, 2010 at 3:25 pm

    Haha but that isn't really what THESE kind of steroids have to do with and that is the point I was trying to make here,

  • January 3, 2011 at 7:04 pm

    I did not like the solu-medrol infusions at all, and do not think they made enough of a difference to make it worth going through the process. Here was my experience:

  • January 3, 2011 at 10:33 pm

    3 Hours??? Wow! They started me at 2 hour sessions and then after all the nurses complained to my neurologist that it was too long of an infusion (since it wasn't giving me headaches)they bumped me down to 1 hour a day!

    I got a bit of the Roid Rage in the following weeks but I had also been on Prednisone non-stop since August. So the first solu-medrol infusion I had wasnt that bad, in fact it helped a lot but this last one just made me more angry and stressed so I don'tknow if it has done much to help.

    I am almost tapered off the Prednisone and I am so glad because I want to be on the least amount of meds I can… I'm really starting to believe the key to this staying healthy thing is going to be diet for me. Going to stock up on the "Naked" juices!


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